Questions:

1. Why it is worth speaking about breast cancer in older women?
2. Which is in your opinion the major challenge a medical oncologist have to face while treating an older woman with breast cancer and how it can be addressed?
3. Which is today the level of evidence for treating older breast cancer patients? How do you choose among the different available treatments?
4. You have made examples related to the adjuvant setting, do we have the same situation in the metastatic setting
5. What would you recommend in this circumstance, ie. if you have an active agent with no specific data in the older population: are you going to use it in your clinics or do you wait for specific data to come?